产品货号：
Z30415
中文名称：
ZEB2抗体
英文名称：
Anti-ZEB2 Antibody
产品规格：
0.1mg
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ZEB2 Antibody |
| 指标别名 | KIAA0569;SIP 1;SIP1;Smad interacting protein 1;SMADIP1;ZEB2;ZFHX1B;ZFX1B |
| 克隆性 | Polyclonal |
| 检验物种 | human,mouse,rat |
| 应用范围 | ELISA,WB,ICC,IF |
| 基因名称 | ZEB2 |
| 抗体来源 | Rabbit |
| 抗体类型 | IgG |
| 免疫原 | ZEB2 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human ZEB2.The immunogen is located within the last 50 amino acids of ZEB2. |
| 计算分子量 | 136kDa |
| 成分 | ZEB2 Antibody is supplied in PBS containing 0.02% sodium azide. |
| 纯化方式 | ZEB2 Antibody is affinity chromatography purified via peptide column. |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | 4℃可保存3个月，-20℃可保存1年。 |
| 背景资料 | ZEB2,initially identified as Smad interacting-protein 1,is normally located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs.Like the homologous ZEB1,ZEB2 inhibits the transcription of the E-cadherin gene and induces epithelial-mesenchymal transition,a genetic program controlling cell migration during embryonic development and wound healing,in vitro.ZEB2 can also protect cells from DNA damage-induced apoptosis,suggesting that its expression may contribute to tumor progression.Recent evidence has shown that ZEB2 is often observed in the cytoplasm in numerous cancer tissues,indicating that its localization may be regulated in normal and tumor tissues.Mutations in this gene are also associated with Hirschsprung disease/Mowat-Wilson syndrome. |
| Uniprot ID | O60315 |
| 基因名全称 | Zinc finger E-box binding homeobox 2 |
| 蛋白名全称 | Zinc finger E-box binding homeobox 2 |
| 推荐稀释比 | ZEB2 antibody can be used for detection of ZEB2 by Western blot at 1 ～ 2μg/mL.Antibody can also be used for immunocytochemistry starting at 20μg/mL.For immunofluorescence start at 20μg/mL.Antibody validated:Western Blot in mouse samples;Immunocytochemistry in human samples and Immunofluorescence in human samples.All other applications and species not yet tested. |
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